How the NAD+ concentration calculation works
Concentration is the entered vial amount divided by the resulting solution volume. In this arithmetic example, 500 mg in 5 mL is 100 mg/mL. On a U-100 insulin syringe one unit represents 0.01 mL, so this example has 1,000 mcg per unit. An entered amount of 50 mg therefore corresponds to 50 units.
The tables illustrate conversions, not a treatment schedule. They cannot determine whether a product is approved or suitable for human use. Follow product-specific instructions from your qualified prescriber or pharmacist for preparation, dose, device, and storage.
NAD+ conversion examples (500 mg in 5 mL)
| Dose | Units | mL | Doses per vial |
|---|---|---|---|
| 25 mg | 25 | 0.25 | 20 |
| 50 mg | 50 | 0.5 | 10 |
| 100 mg | 100 | 1 | 5 |
Example amounts at 50 mg per dose
| Vial | Water | Concentration | Units per dose | Doses |
|---|---|---|---|---|
| 100 mg | 5 mL | 20 mg/mL | 250 | 2 |
| 500 mg | 5 mL | 100 mg/mL | 50 | 10 |
| 1,000 mg | 5 mL | 200 mg/mL | 25 | 20 |
Each amount shows its unit; the form starts in mg. For a fixed amount and dose, doubling the resulting solution volume halves the concentration and doubles the calculated units. The arithmetic number of doses is unchanged. This relationship does not establish an appropriate preparation volume or syringe for a product.
Worked example
500 mg / 5 mL = 100 mg/mL = 100,000 mcg/mL. One unit = 0.01 mL = 1,000 mcg. 50,000 mcg / 1,000 mcg per unit = 50 units. The vial holds 500,000 / 50,000 = 10 doses, which at 3 per week is about 23 days.
See the general peptide reconstitution calculator for the formulas and mg-to-mcg conversions, and our calculator methodology and limitations. The FDA's report on compounded semaglutide dosing errors explains why concentration, units, and measurement instructions need to be confirmed with a health care provider or compounder.