How to reconstitute TB-500
TB-500 is sold as a freeze-dried powder, most often in 2 mg, 5 mg, 10 mg vials. Add bacteriostatic water, let it dissolve without shaking, and the concentration is the vial amount divided by the water: 5 mg in 2 mL is 2.5 mg/mL. On a U-100 insulin syringe one unit is 0.01 mL, so each unit carries 25 mcg, and a 2.5 mg dose is 100 units.
Not approved for human use. Commonly cited protocols use 2 to 5 mg twice a week for a loading period, then less often. Nothing on this page is a dosing recommendation; the calculator converts a dose you already have into syringe units.
TB-500 doses in syringe units (5 mg vial, 2 mL water)
| Dose | Units | mL | Doses per vial |
|---|---|---|---|
| 2 mg | 80 | 0.8 | 2 |
| 2.5 mg | 100 | 1 | 2 |
| 5 mg | 200 | 2 | 1 |
Vial sizes at 2.5 mg per dose
| Vial | Water | Concentration | Units per dose | Doses |
|---|---|---|---|---|
| 2 mg | 2 mL | 1 mg/mL | 250 | 0 |
| 5 mg | 2 mL | 2.5 mg/mL | 100 | 2 |
| 10 mg | 2 mL | 5 mg/mL | 50 | 4 |
The dose column is in mg. Doubling the water halves the concentration and doubles the units per dose; the number of doses in the vial never changes. If a dose comes out under 5 units, use less water so it is easier to measure. If it exceeds the syringe, use more water or a bigger syringe.
Worked example
5 mg / 2 mL = 2.5 mg/mL = 2,500 mcg/mL. One unit = 0.01 mL = 25 mcg. 2,500 mcg / 25 mcg per unit = 100 units. The vial holds 5,000 / 2,500 = 2 doses, which at 2 per week is about 7 days.
See the general peptide calculator for the formulas, syringe sizes, and the common mg versus mcg mistakes.